Adenosine A3 Receptor anticorps

N° du produit ABIN317625

Cet anticorps anti-Adenosine A3 Receptor est un anticorps Lapin Polyclonal détectant Adenosine A3 Receptor dans WB, IF, IHC (p) et EIA. Adapté pour Humain.

Aperçu rapide pour Adenosine A3 Receptor anticorps (ABIN317625)

Antigène: Adenosine A3 Receptor (ADORA3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenosine A3 Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Adenosine A3 Receptor anticorps

Specificité: This antibody detects endogenous levels of Adenosine A3-R protein.(region surrounding Glu318)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Adenosine A3 Receptor

Antigène: Adenosine A3 Receptor (ADORA3)

Autre désignation: Adenosine Receptor A3

Sujet: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFalpha and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA3, Adenosine A3 receptor

Poids moléculaire: approx. 38 kDa

ID gène: 140

NCBI Accession: NP_000668

UniProt: P33765

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process